IV Ozone Therapy (Major Autohemotherapy or MAH for short) has been gaining a lot of traction in the Functional Medicine world. Ozone is a naturally occurring gas comprised of 3 oxygen atoms. It makes up part of the earth’s atmosphere (ozone in the atmosphere is what makes the sky look blue), and it protects us from UV radiation. Ozone was discovered in the 1840’s, and during WWI doctors used it to clean and disinfect wounds.

When infused into the bloodstream, ozone has several potential benefits especially when if comes to regulating immune function. This makes it beneficial both for overactive immune system states, i.e. autoimmune diseases, as well as the under-active immune systems associated with cancer and chronic infections.

Ozone therapy works to increase antioxidant activity in the body, helping to quench free radicals and inflammation. It does this by providing a controlled amount of oxidative stress, and in response the body increases its own internal antioxidant production. Another mechanism whereby ozone therapy delivers its health benefits is by stimulating the mitochondria, the energy-producing powerhouses of the cells.

indications and potential benefits 

IV Ozone Therapy is a safe and effective therapy with a multitude of potential benefits. It’s been a game-changer for patients dealing with a wide range of chronic conditions. Some of its notable benefits include:

Heart Disease and Circulatory Disorders

Ozone increases update of oxygen and improves blood flow, making in a promising treatment for cardiovascular conditions.

Chronic Infections, including Lyme Disease

Clinicians have been using ozone therapy for decades to successfully treat viral and bacteria infections, including Lyme Disease.


2019 study of 65 patients with fibromyalgia found that ozone therapy provided significant relief of the chronic pain and other symptoms associated with fibromyalgia without side effects.

Macular Degeneration

Conventional medicine lacks solutions when it comes to treating macular degeneration, but Dr. Schallenberger, who has used ozone in his practice for over 30 years, reports that in all the cases he treated the patients’ deterioration ceased, and the majority actually saw improvements in their vision.


Ozone therapy makes an excellent addition to a cancer treatment protocol because of its ability to counteract the decreased oxygen utilization that is a key feature of cancer.

Autoimmune Diseases, including Rheumatoid Arthritis

 This 2016 paper describes the use of ozone therapy for RA, concluding that, “ozone is an effective and reliable complementary therapy that can used in treatment of RA.” Ozone therapy is also successfully used for patients with MS.

Long covid

Many of the symptoms of long Covid are similar to symptoms of other conditions that ozone therapy is known to help, such as Chronic Fatigue Syndrome. Ozone can address the lung fibrosis often seen in long Covid sufferers, and ozone is also antithrombotic, meaning it can help prevent microclotting. Ozone’s antiviral properties make it a helpful therapy in cases where Covid has reactivated old infections like Lyme or Epstein Barr.

iv ozone therapy administration 

IV Ozone Therapy is simple and easy to receive. The patient sits in a comfy recliner, and a healthcare provider removes several ounces of blood, places it in a sterilized bottle, and difuses ozone into it. The provider then inserts an IV line into a vein on the forearm and returns the ozone-enriched blood to the patient’s bloodstream. The therapy takes about 60 minutes to complete, and while you’re receiving it you can read, work on a laptop, or listen to relaxing music or a guided meditation. Afterwards, the staff removes the IV from your arm, and you are set to go about the rest of your day with a new boost of energy and vitality. When properly administered, ozone therapy has an excellent safety record.

iv ozone therapy at grassroots 

Ready to give Ozone Therapy a try for yourself? You can experience first-hand the life-changing benefits of this innovative and integrative therapy at GrassRoots Functional Medicine. To participate in IV Ozone, you do not have to be an Adaptation Program Patient. We will simply have you set up a consult prior to the treatment, draw some basic labs to make sure there are no contraindications to the therapy, and if you are a good fit we will schedule your first therapy!

If you want to dive deeper and take a comprehensive appraoach to your health, start by reviewing our Adaptation Programs page and a scheduling a Free Discovery Call to reclaim the vitality you once knew!

*Disclaimer: Ozone therapy is not an FDA approved therapy. You should consult your medical practitioner before attempting anything to do with ozone therapy. The information in this document is not intended to treat, diagnose, or cure. It is not a substitute for medical advice.

About the Author: Dr. Seth Osgood is a Doctor of Nursing Practice, Board Certified Family Nurse Practitioner and Institute of Functional Medicine (IFM) Certified Practitioner. Dr. Osgood received his post-graduate training in Functional Medicine through the IFM and from working with Dr. Amy Myers. He has helped people from around the world improve their health utilizing a Functional Medicine approach.